Skip to content
PatentBrief
Get alertsTop ↑

How to Take 3D Pictures Inside Human Tissue Using Near-Infrared Light

A system that uses flexible fiber optic cables to map the inside of complex body parts by shining light through them and measuring how it scatters.

Granted 2005ExpiredExpired 2022Owned by Research Foundation of the State University of New YorkInvented by Randall L. Barbour

Original patent title: “USRE38800E1 - NIR clinical opti-scan system

Plain-English explanation by SahiLast reviewed · June 15, 2026

A system that uses flexible fiber optic cables to map the inside of complex body parts by shining light through them and measuring how it scatters. Granted to Research Foundation of the State University of New York in 2005 with 42 claims and 25 forward citations.

Key facts

Patent numberUS RE38800
StatusExpired
FieldBiotech & Medicine
AssigneeResearch Foundation of the State University of New York
InventorRandall L. Barbour
Filed2002
Granted2005
Claims42
Times cited25
LitigationNone on record
Value · $32K$104KMinimal

Coverage

What does this patent actually cover?

This patent describes a way to create 3D images of internal body structures by shining near-infrared light into tissue and collecting the light that bounces back out. It uses an adjustable support structure, like a flexible frame, that holds a large array of fiber optic cables against the uneven surface of a body part. These fibers act as both the light source and the light collector, allowing the system to capture data from many different points simultaneously. A detector then measures this scattered light, and a computer uses that data to calculate what the internal tissue looks like in three dimensions.

The gap

What does this patent NOT cover?

  • Does not cover imaging techniques that rely on X-rays or ionizing radiation.
  • Does not cover systems that lack the specific adjustable fiber-holding assembly for irregular surfaces.
  • Does not cover ultrasound or MRI-based imaging methods.
  • Does not cover imaging that requires invasive surgical entry into the body.

These exclusions are unique to PatentBrief — derived from the actual claim language, not patent-office boilerplate.

What made this novel

The innovation lies in the adjustable fiber array that physically conforms to the non-uniform, curved surface of a body part, ensuring consistent contact and data collection across complex shapes.

USRE38800E1 - NIR clinical opt…(Primary claim)biotechmedical devicesconsumer electronics

Schematic visualization of the patent's claim structure. Hand-drawn diagrams in progress for each landmark patent.

Where you've seen this

Real-world examples

01

Optical breast imaging systems

02

Near-infrared diffuse optical tomography (DOT) scanners

03

Non-invasive tissue diagnostic devices

Why it matters

The bigger picture

This technology is significant because it provides a non-invasive way to look inside soft tissue, which is often difficult to image clearly with traditional methods. By using near-infrared light, it can detect differences in how light is absorbed or scattered by different types of tissue, potentially helping to identify tumors or other abnormalities without exposing the patient to harmful radiation.

Filed

June 27, 2002

Granted

September 20, 2005

Market context

Who's building on this

Companies in this space

Research institutions and medical device companies focused on diffuse optical tomography (DOT) continue to refine these concepts. The original assigneeassigneeThe entity that owns the patent — usually the inventor's employer or a company.Read more →, the Research Foundation of the State University of New York, has been a key player in advancing this specific approach to optical imaging.

Market impact

This patent helped formalize the hardware requirements for practical optical tomography, moving it from a theoretical physics concept toward a deployable medical diagnostic tool. It established a framework for using flexible fiber arrays to solve the problem of imaging irregular biological surfaces, influencing subsequent designs in non-invasive diagnostic equipment.

Claim 1 — Plain English

What this patent covers

This patent describes a way to create 3D images of internal body structures by shining near-infrared light into tissue and collecting the light that bounces back out. It uses an adjustable support structure, like a flexible frame, that holds a large array of fiber optic cables against the uneven surface of a body part. These fibers act as both the light source and the light collector, allowing the system to capture data from many different points simultaneously. A detector then measures this scattered light, and a computer uses that data to calculate what the internal tissue looks like in three dimensions.

The clever bit

The innovation lies in the adjustable fiber array that physically conforms to the non-uniform, curved surface of a body part, ensuring consistent contact and data collection across complex shapes.

What it does not cover

  • Does not cover imaging techniques that rely on X-rays or ionizing radiation.
  • Does not cover systems that lack the specific adjustable fiber-holding assembly for irregular surfaces.
  • Does not cover ultrasound or MRI-based imaging methods.
  • Does not cover imaging that requires invasive surgical entry into the body.

Patent timeline

Filing

Application submitted to the patent office

Publication

Application published, typically 18 months after filing

Grant

Patent officially issued

PatentBrief Score

Impact Score

Strong

Citation count

28/40

Moderately cited

Claim breadth

20/20

Very broad protection

Recency

0/20

Older than 20 years

Assignee scale

20/20

Major company or institution

PatentBrief Impact Score — based on citation count, claim breadth, recency, and assignee scale. Not a legal assessment.

Heuristic Value Estimate

What this patent might be worth

Minimal

$32K$104K

Midpoint $65K · expired or expiring · industry ×1.5

Adjust inputs →

Heuristic only — blends forward/backward citation counts, claim scope, time remaining, litigation history, and CPC-derived industry baseline. Real valuations need a professional appraisal.

The original legal language

Original claims

42 claims as filed with the patent office.

Concepts involved

ClaimPrior artNon-obviousnessNoveltySpecificationAssigneePatent term

Citations

Patent lineage

Cites earlier patents

6

earlier patents this invention cites as foundations

View prior art →

Cited by later patents

25

later patents that build on this invention

View patents →

Cite this patent

Barbour, R. L. (2005). How to Take 3D Pictures Inside Human Tissue Using Near-Infrared Light (U.S. Patent No. RE38,800). U.S. Patent and Trademark Office. https://patentbrief.org/patent/us/RE38800/digital-video-recorder-dvr

Auto-generated from the patent record. Double-check author order and the issue date against the official USPTO document before submitting.

Embed

Add this patent to your site

Drop this plain-English patent card into any blog post or article — free, no signup. It always links back to the full breakdown here.

<div data-patentlens-widget data-patent-number="USRE38800"></div>
<script src="https://patentbrief.org/embed.js" async></script>

Stay in the loop

Get a weekly digest of new patents.

One email per week. No spam. Unsubscribe anytime.

Keep exploring

Related patents you should know

US 4683195 · 1987

How to Make Billions of Copies of a DNA Segment

This patent describes the Polymerase Chain Reaction (PCR), a method to rapidly create many copies of a specific piece of DNA or RNA, enabling its detection and analysis.

Cetus Corp

US 8697359 · 2014

How to Edit Genes in Human Cells Using an Engineered CRISPR System

This patent describes an engineered CRISPR-Cas9 system for precisely cutting DNA in eukaryotic cells to change how genes work, opening the door for gene editing in complex organisms.

Massachusetts Institute of Technology

US 7657849 · 2010

How the iPhone's Slide-to-Unlock Gesture Works

Apple's 2010 patent describes unlocking a device by dragging a specific graphical image across the touchscreen along a predefined path, a gesture that became iconic with the original iPhone.

Apple Inc

US 4733665 · 1988

How Doctors Implant a Permanent Stent Using a Balloon

This patent describes the method for placing a permanent, expandable wire mesh tube inside a blood vessel or other body tube using a balloon-tipped catheter to widen it and keep it open.

Expandable Grafts Partnership

US 4965188 · 1990

How to Make Many Copies of a DNA Piece with Heat

This patent describes the Polymerase Chain Reaction (PCR) method, a technique to make millions of copies of a specific DNA segment using a heat-resistant enzyme and repeated temperature changes.

Cetus Corp

US 4235871 · 1980

How to Encapsulate Active Materials in Lipid Bubbles Efficiently

This patent describes a method for trapping biologically active substances inside tiny, multi-layered fat bubbles called liposomes, using a specific water-in-oil emulsion and gel-forming process to improve how much material gets captured.

Individual

More to explore

More in Biotech & Medicine

Browse all Biotech & Medicine

New to patents?

What is a patent?How to read a patentAnatomy of a claimHow strong is this patent?What the citations meanWhat it doesn't coverBiotech PatentsPatent glossary

Common Questions

Frequently Asked Questions

What does How to Take 3D Pictures Inside Human Tissue Using Near-Infrared Light cover?

A system that uses flexible fiber optic cables to map the inside of complex body parts by shining light through them and measuring how it scatters.

Who owns patent US RE38800?

Research Foundation of the State University of New York owns this patent, granted in 2005.

When does this patent expire?

This patent has expired and is now in the public domain — anyone can use the invention freely.

What is patent US RE38800 cited by?

This patent has been cited by 25 later patents that build on its ideas.

What problem does this patent solve?

This technology is significant because it provides a non-invasive way to look inside soft tissue, which is often difficult to image clearly with traditional methods. By using near-infrared light, it can detect differences in how light is absorbed or scattered by different types of tissue, potentially helping to identify tumors or other abnormalities without exposing the patient to harmful radiation.

What does this patent NOT cover?

Does not cover imaging techniques that rely on X-rays or ionizing radiation.

Patent monitoring

Get notified when Research Foundation of the State University of New York files a new patent

Get notified when this company files a new patent. Weekly digest · Confirm via email · Unsubscribe anytime.

Last reviewed: June 15, 2026 · PatentBrief is not a law firm and this is not legal advice.