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PatentBrief

Subject matter

What can — and can't — be patented?

Before novelty or cost, your invention has to be the kind of thing patents cover at all. Here's the straight answer for the things people most often ask about — software, algorithms, business methods, genes, recipes — with the rule and the case behind each.

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Generally patentable

A drug or chemical compound

Yes — patentable

Yes. A new, non-obvious, useful chemical compound or formulation is squarely patentable subject matter.

Example · A newly synthesized molecule, or a novel formulation of a known drug, is classic eligible subject matter.

Rule · New compositions of matter made by people are eligible under §101.

A machine or physical device

Yes — patentable

Yes. Machines, mechanical devices, and physical apparatus are core patentable subject matter.

Example · A new engine component, surgical instrument, or consumer gadget mechanism.

Rule · Machines and manufactures are two of the four statutory categories.

A manufacturing or industrial process

Yes — patentable

Yes. A novel, non-obvious process that transforms materials into a different state or thing is eligible.

Example · The rubber-curing process in Diamond v. Diehr — even though it used a math formula.

Rule · Processes are a statutory category; transformation of an article is a strong signal.

The look of a product (design)

Yes — patentable

Yes — but through a design patent, which protects ornamental appearance, not a utility patent.

Example · The shape of a bottle or the graphical layout of an icon — protected by a design patent for 15 years from grant.

Rule · Ornamental designs are eligible under the separate design-patent statute (§171).

A new plant variety

Yes — patentable

Yes. A distinct, new plant variety reproduced asexually can be protected by a plant patent.

Example · A new cultivar of rose or apple, propagated by cuttings or grafting.

Rule · Asexually-reproduced plant varieties are eligible under the plant-patent statute (§161).

It depends

Software

It depends

Yes — if the claim is tied to a specific technical improvement, not just an abstract idea running on a generic computer.

Example · A new data structure that makes a database faster (eligible, like Enfish) versus 'use a computer to manage escrow' (ineligible, like Alice).

Rule · Alice step one: is it directed to an abstract idea, or to an improvement in technology?

A business method

It depends

Difficult. A pure method of organizing human activity is an abstract idea; it needs a genuine technical component to survive.

Example · Hedging risk was ineligible in Bilski v. Kappos. A method that also solves a concrete technical problem stands a better chance.

Rule · Methods of organizing human activity are abstract ideas under the 2019 PEG.

An app or website idea

It depends

You can't patent the idea — only a specific, novel, non-obvious technical implementation of it.

Example · 'An app that connects dog walkers' is an unprotectable idea; a new technical mechanism inside it might be patentable.

Rule · Ideas and results are not patentable; concrete implementations can be.

An AI / machine-learning model

It depends

Yes, when claimed as a specific technical application or improvement — not as the abstract math of the model itself.

Example · A novel training technique that improves hardware efficiency is more defensible than 'a neural network that predicts X.'

Rule · The model's math is abstract; a concrete technical use can supply eligibility.

A gene or DNA sequence

It depends

Isolated, naturally-occurring DNA is not patentable; synthetic cDNA and engineered sequences are.

Example · In AMP v. Myriad, isolated BRCA genes were ineligible products of nature, but lab-made cDNA was eligible.

Rule · Products of nature are excluded; human-made variants with new characteristics are not.

A recipe or food

It depends

Rarely as a recipe. A simple list of ingredients is usually obvious; a genuinely novel composition or process can qualify.

Example · An ordinary recipe fails on obviousness; a new shelf-stable formulation or a non-obvious process may pass.

Rule · Eligible in principle, but recipes usually fail novelty (§102) or non-obviousness (§103).

Excluded — not patentable

An algorithm or math formula

No — excluded

Not on its own. A mathematical algorithm or formula claimed in the abstract is a classic judicial exception.

Example · Converting numbers between formats was unpatentable in Gottschalk v. Benson — but applying a formula to cure rubber was eligible in Diehr.

Rule · Mathematical concepts are abstract ideas; eligibility needs a practical application.

A diagnostic method

No — excluded

Usually not. A method that just detects a natural correlation, using conventional steps, is ineligible.

Example · Correlating metabolite levels with dosage was ineligible in Mayo v. Prometheus.

Rule · Laws of nature plus routine, conventional steps are not patentable.

A scientific principle or law of nature

No — excluded

No. Laws of nature, natural phenomena, and abstract scientific truths belong to everyone.

Example · You could not patent E=mc², gravity, or a newly-discovered natural correlation by itself.

Rule · Laws of nature and natural phenomena are core judicial exceptions.

These are the general rules, not legal advice. Eligibility is fact-specific and shifts with new decisions — and even an eligible invention still has to be novel and non-obvious. For your specific idea, talk to a registered patent attorney. PatentBrief is not a law firm.

Keep going · Patent eligibility

Patent Eligibility (§101)The two-step Alice/Mayo test, explained from scratch.Eligibility CheckRun your invention through the test for a reasoned verdict.Landmark §101 CasesAlice, Mayo, Diehr, Bilski, Myriad — the decisions that drew the line.How to Patent SoftwareDrafting software claims that survive the §101 Alice test.Can You Patent an AI Invention?What clears §101 for AI, and who can be named inventor.