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Seeing Blood Flow Deep Inside Tissue Without Touching It

This patent describes a way to create 3D images of blood flow up to 1.5 cm deep inside body tissue using near-infrared light, all without any physical contact with the skin.

Granted 2018ActiveExpires 2036Owned by University of Kentucky Research FoundationInvented by Yu Lin, Chong Huang, Guoqiang Yu

Original patent title: “Noncontact three-dimensional diffuse optical imaging of deep tissue blood flow distribution

Plain-English explanation by SahiLast reviewed · September 9, 2026

This patent describes a way to create 3D images of blood flow up to 1.5 cm deep inside body tissue using near-infrared light, all without any physical contact with the skin. Granted to University of Kentucky Research Foundation in 2018 with 13 claims and 5 forward citations, and it is expected to expire in 2036.

Coverage

What does this patent actually cover?

This patent details an optical method for creating three-dimensional (3D) images of blood flow in deep tissue, specifically up to about 1.5 cm, without needing to touch the tissue (ClaimclaimA numbered sentence at the end of a patent that legally defines what the inventor owns. The most important section.Read more → 1). It works by projecting near-infrared light from long-coherence laser sources onto the tissue surface through optical lenses. A detector array then captures the diffused near-infrared light reflected back, also through lenses (Claim 1). The collected data is then processed, often using a finite-element-method (FEM), to reconstruct a 3D image of the blood flow distribution (Claim 6). For example, a surgeon could use this system to check the blood supply in a delicate skin graft during surgery without disturbing the healing tissue.

The gap

What does this patent NOT cover?

  • Does not cover imaging methods that require physical contact between the imaging probe or detector and the tissue (ClaimclaimA numbered sentence at the end of a patent that legally defines what the inventor owns. The most important section.Read more → 1).
  • Does not cover imaging deeper than approximately 1.5 cm into the tissue (ClaimclaimA numbered sentence at the end of a patent that legally defines what the inventor owns. The most important section.Read more → 1).
  • Does not cover imaging techniques that use light outside the near-infrared spectrum (ClaimclaimA numbered sentence at the end of a patent that legally defines what the inventor owns. The most important section.Read more → 1).
  • Does not cover two-dimensional (2D) imaging; it specifically focuses on three-dimensional (3D) image reconstruction (ClaimclaimA numbered sentence at the end of a patent that legally defines what the inventor owns. The most important section.Read more → 1).
  • Does not cover methods that do not use optical lenses for both applying and detecting the light (ClaimclaimA numbered sentence at the end of a patent that legally defines what the inventor owns. The most important section.Read more → 1).

These exclusions are unique to PatentBrief — derived from the actual claim language, not patent-office boilerplate.

Key facts

Patent numberUS 9861319
StatusActive
FieldBiotech & Medicine
AssigneeUniversity of Kentucky Research Foundation
InventorsYu Lin, Chong Huang, Guoqiang Yu
Filed2016
Granted2018
Expires2036
Claims13
Times cited5
LitigationNone on record
Value · $66K$211KModest

What made this novel

The noveltynoveltyThe requirement that an invention be different from anything publicly known before its priority date.Read more → lies in combining non-contact near-infrared light application and detection with advanced 3D image reconstruction techniques, such as the finite-element-method, to accurately map deep tissue blood flow in tissues with arbitrary shapes. This allows for safe, detailed analysis of vulnerable or sensitive tissues.

The Patent Drawing

Representative patent drawing for Noncontact three-dimensional diffuse optical imaging of deep tissue blood flow distribution (US 9861319)
Representative figure · US 9861319All figures on Google Patents →
Noncontact three-dimensional d…(Primary claim)medical devicesbiotechsoftwareconsumer electronics

Schematic visualization of the patent's claim structure. Hand-drawn diagrams in progress for each landmark patent.

Where you've seen this

Real-world examples

01

Monitoring blood flow in tissue flaps during reconstructive surgery

02

Assessing healing and circulation in burn wounds without direct contact

03

Evaluating blood supply in diabetic foot ulcers

04

Observing tissue perfusion during organ transplantation procedures

05

Research tools for studying microcirculation in biological tissues

Why it matters

The bigger picture

This technology is important because it allows medical professionals to assess blood flow in sensitive, vulnerable, or damaged tissues without physical contact. This non-contact approach reduces the risk of infection, further injury, or disruption to healing processes. It is particularly valuable for monitoring open wounds, surgical sites, or delicate tissue grafts where traditional contact-based methods would be problematic.

Filed

March 23, 2016

Granted

January 9, 2018

Market context

Who's building on this

Companies in this space

Companies specializing in medical imaging, surgical tools, and non-invasive diagnostics are likely developing or using similar technologies. This includes major medical device manufacturers like Canon Medical Systems and Siemens Healthineers, as well as various startups focused on optical coherence tomography (OCT) or diffuse optical tomography (DOT) for clinical applications. The University of Kentucky Research Foundation, as the assigneeassigneeThe entity that owns the patent — usually the inventor's employer or a company.Read more →, may also continue to licenselicensePermission from the patent owner to make, use, or sell the invention — usually in exchange for payment. Doesn't transfer ownership.Read more → or develop this technology for new applications.

Market impact

This patent contributes to the growing field of non-invasive medical diagnostics, particularly for monitoring tissue viability and perfusion. By enabling non-contact 3D imaging of blood flow, it offers a safer and less disruptive alternative to traditional contact-based methods. This could lead to improved patient outcomes in surgeries involving tissue grafts, wound care, and other areas where precise, gentle blood flow assessment is crucial, potentially expanding the market for advanced optical imaging devices in clinical settings.

Claim 1 — Plain English

What this patent covers

This patent details an optical method for creating three-dimensional (3D) images of blood flow in deep tissue, specifically up to about 1.5 cm, without needing to touch the tissue (Claim 1). It works by projecting near-infrared light from long-coherence laser sources onto the tissue surface through optical lenses. A detector array then captures the diffused near-infrared light reflected back, also through lenses (Claim 1). The collected data is then processed, often using a finite-element-method (FEM), to reconstruct a 3D image of the blood flow distribution (Claim 6). For example, a surgeon could use this system to check the blood supply in a delicate skin graft during surgery without disturbing the healing tissue.

The clever bit

The novelty lies in combining non-contact near-infrared light application and detection with advanced 3D image reconstruction techniques, such as the finite-element-method, to accurately map deep tissue blood flow in tissues with arbitrary shapes. This allows for safe, detailed analysis of vulnerable or sensitive tissues.

What it does not cover

  • Does not cover imaging methods that require physical contact between the imaging probe or detector and the tissue (Claim 1).
  • Does not cover imaging deeper than approximately 1.5 cm into the tissue (Claim 1).
  • Does not cover imaging techniques that use light outside the near-infrared spectrum (Claim 1).
  • Does not cover two-dimensional (2D) imaging; it specifically focuses on three-dimensional (3D) image reconstruction (Claim 1).
  • Does not cover methods that do not use optical lenses for both applying and detecting the light (Claim 1).

Patent timeline

Filing

Application submitted to the patent office

Publication

Application published, typically 18 months after filing

Grant

Patent officially issued

Expiration

Patent enters public domain

PatentBrief Score

Impact Score

Moderate

Citation count

16/40

Early citations

Claim breadth

9/20

Moderate scope

Recency

10/20

Granted 5–10 years ago

Assignee scale

20/20

Major company or institution

PatentBrief Impact Score — based on citation count, claim breadth, recency, and assignee scale. Not a legal assessment.

Heuristic Value Estimate

What this patent might be worth

Modest

$66K$211K

Midpoint $132K · 9.5 yr remaining · industry ×2.2

Adjust inputs →

Heuristic only — blends forward/backward citation counts, claim scope, time remaining, litigation history, and CPC-derived industry baseline. Real valuations need a professional appraisal.

Patent Claims

0 independent claims · 1 dependent

Claims are the legal boundaries of the patent. An independent claim stands alone. A dependent claim adds limitations to its parent, narrowing — but not broadening — the scope.

The original legal language

Original claims

13 claims as filed with the patent office.

Concepts involved

ClaimPrior artNon-obviousnessNoveltySpecificationAssigneePatent term

Citations

Patent lineage

Cites earlier patents

20

earlier patents this invention cites as foundations

View prior art →

Cited by later patents

5

later patents that build on this invention

View patents →

Cite this patent

Lin, Y., Huang, C., & Yu, G. (2018). Seeing Blood Flow Deep Inside Tissue Without Touching It (U.S. Patent No. 9,861,319). U.S. Patent and Trademark Office. https://patentbrief.org/patent/us/9861319/noncontact-three-dimensional-diffuse-optical-imaging-of-deep-tissue-blood-flow-d

Auto-generated from the patent record. Double-check author order and the issue date against the official USPTO document before submitting.

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Common Questions

Frequently Asked Questions

What does Seeing Blood Flow Deep Inside Tissue Without Touching It cover?

This patent describes a way to create 3D images of blood flow up to 1.5 cm deep inside body tissue using near-infrared light, all without any physical contact with the skin.

Who owns patent US 9861319?

University of Kentucky Research Foundation owns this patent, granted in 2018.

When does this patent expire?

This patent is expected to expire on March 23, 2036, when the invention enters the public domain.

What is patent US 9861319 cited by?

This patent has been cited by 5 later patents that build on its ideas.

What problem does this patent solve?

This technology is important because it allows medical professionals to assess blood flow in sensitive, vulnerable, or damaged tissues without physical contact. This non-contact approach reduces the risk of infection, further injury, or disruption to healing processes. It is particularly valuable for monitoring open wounds, surgical sites, or delicate tissue grafts where traditional contact-based methods would be problematic.

What does this patent NOT cover?

Does not cover imaging methods that require physical contact between the imaging probe or detector and the tissue (Claim 1).

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Last reviewed: September 9, 2026 · PatentBrief is not a law firm and this is not legal advice.