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How Auto-Injectors Adjust Their Dose Using a Simple Spacer

A 1977 invention for auto-injectors that uses a physical spacer to adjust the amount of medicine inside the device before it is fired.

Granted 1977ExpiredExpired 1996Owned by Survival Technology IncInvented by Sheldon Kaplan, George B. Calkins, Stanley J. Sarnoff + 1 more

Original patent title: “Hypodermic injection device having means for varying the medicament capacity thereof

Plain-English explanation by SahiLast reviewed · June 13, 2026

A 1977 invention for auto-injectors that uses a physical spacer to adjust the amount of medicine inside the device before it is fired. Granted to Survival Technology Inc in 1977 with 7 claims and 108 forward citations, and it is now in the public domain.

Key facts

Patent numberUS 4031893
StatusExpired
FieldBiotech & Medicine
AssigneeSurvival Technology Inc
InventorsSheldon Kaplan, George B. Calkins, Stanley J. Sarnoff and 1 other
Filed1976
Granted1977
Expires1996 (expired)
Claims7
Times cited108
LitigationNone on record
Value · $99K$317KModest

Coverage

What does this patent actually cover?

This patent describes an auto-injector mechanism that allows the same device to hold different amounts of liquid medication. It achieves this by placing a spacer between the spring-loaded plunger and the piston inside the medicine cartridge. By changing the thickness or presence of this spacer, the piston is pushed further into the cartridge, effectively shrinking the volume of the medicament chamber. This ensures that the device can be calibrated for specific doses without needing to redesign the entire spring-power assembly.

The gap

What does this patent NOT cover?

  • Does not cover electronic or digital dose-setting mechanisms
  • Does not cover devices that use multiple chambers to mix medications
  • Does not cover needle-free jet injection systems
  • Does not cover the internal spring-power release mechanism itself

These exclusions are unique to PatentBrief — derived from the actual claim language, not patent-office boilerplate.

What made this novel

By using a spacer to pre-position the piston, the inventors decoupled the dose volume from the stroke length of the spring-powered plunger, allowing a single injector platform to be highly versatile.

The Patent Drawing

Representative patent drawing for Hypodermic injection device having means for varying the medicament capacity thereof (US 4031893)
Representative figure · US 4031893All figures on Google Patents →
Hypodermic injection device ha…(Primary claim)biotechmechanicalconsumer electronics

Schematic visualization of the patent's claim structure. Hand-drawn diagrams in progress for each landmark patent.

Where you've seen this

Real-world examples

01

EpiPen style emergency auto-injectors

02

Military nerve agent antidote injectors

03

Single-use pre-filled medication syringes

Why it matters

The bigger picture

This design was critical for the mass production of emergency auto-injectors, such as those used for nerve agent antidotes or epinephrine. It allowed manufacturers to use a standardized spring-loaded gun body while customizing the dose for different patient needs or drug concentrations using simple, interchangeable mechanical spacers.

Filed

May 14, 1976

Granted

June 28, 1977

Market context

Who's building on this

Companies in this space

Survival Technology Inc. was a pioneer in this space, and their work laid the foundation for modern auto-injector platforms. Today, major pharmaceutical and medical device companies like Pfizer, Mylan, and Becton Dickinson continue to refine these mechanical delivery systems for self-administration.

Market impact

This patent helped standardize the manufacturing of reliable, single-use emergency injectors. It enabled the widespread deployment of pre-filled, dose-specific injectors that could be safely used by non-medical personnel in high-stress environments.

Claim 1 — Plain English

What this patent covers

This patent describes an auto-injector mechanism that allows the same device to hold different amounts of liquid medication. It achieves this by placing a spacer between the spring-loaded plunger and the piston inside the medicine cartridge. By changing the thickness or presence of this spacer, the piston is pushed further into the cartridge, effectively shrinking the volume of the medicament chamber. This ensures that the device can be calibrated for specific doses without needing to redesign the entire spring-power assembly.

The clever bit

By using a spacer to pre-position the piston, the inventors decoupled the dose volume from the stroke length of the spring-powered plunger, allowing a single injector platform to be highly versatile.

What it does not cover

  • Does not cover electronic or digital dose-setting mechanisms
  • Does not cover devices that use multiple chambers to mix medications
  • Does not cover needle-free jet injection systems
  • Does not cover the internal spring-power release mechanism itself

Patent Journey

From filing to expiry

PatentBrief Score

Impact Score

Moderate

Citation count

40/40

Highly cited

Claim breadth

5/20

Moderate scope

Recency

0/20

Older than 20 years

Assignee scale

0/20

Independent or smaller assigneeassigneeThe entity that owns the patent — usually the inventor's employer or a company.Read more →

PatentBrief Impact Score — based on citation count, claim breadth, recency, and assignee scale. Not a legal assessment.

Heuristic Value Estimate

What this patent might be worth

Modest

$99K$317K

Midpoint $198K · expired or expiring · industry ×2.2

Adjust inputs →

Heuristic only — blends forward/backward citation counts, claim scope, time remaining, litigation history, and CPC-derived industry baseline. Real valuations need a professional appraisal.

The original legal language

Original claims

7 claims as filed with the patent office.

Concepts involved

ClaimPrior artNon-obviousnessNoveltySpecificationAssigneePatent term

Citations

Patent lineage

Cites earlier patents

7

earlier patents this invention cites as foundations

View prior art →

Cited by later patents

108

later patents that build on this invention

View patents →

Cite this patent

Kaplan, S., Calkins, G. B., Sarnoff, S. J., & Dalling, N. L. (1977). How Auto-Injectors Adjust Their Dose Using a Simple Spacer (U.S. Patent No. 4,031,893). U.S. Patent and Trademark Office. https://patentbrief.org/patent/us/4031893/epipen-autoinjector-kaplan

Auto-generated from the patent record. Double-check author order and the issue date against the official USPTO document before submitting.

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Common Questions

Frequently Asked Questions

What does How Auto-Injectors Adjust Their Dose Using a Simple Spacer cover?

A 1977 invention for auto-injectors that uses a physical spacer to adjust the amount of medicine inside the device before it is fired.

Who owns patent US 4031893?

Survival Technology Inc owns this patent, granted in 1977.

When does this patent expire?

This patent has expired and is now in the public domain — anyone can use the invention freely.

What is patent US 4031893 cited by?

This patent has been cited by 108 later patents that build on its ideas.

What problem does this patent solve?

This design was critical for the mass production of emergency auto-injectors, such as those used for nerve agent antidotes or epinephrine. It allowed manufacturers to use a standardized spring-loaded gun body while customizing the dose for different patient needs or drug concentrations using simple, interchangeable mechanical spacers.

What does this patent NOT cover?

Does not cover electronic or digital dose-setting mechanisms

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Last reviewed: June 13, 2026 · PatentBrief is not a law firm and this is not legal advice.