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How Polystyrene Sulfonate Helps Treat Dry Eye Symptoms

A 1975 patent for an eye drop solution that uses a specific polymer to lubricate and cushion the eye, especially for contact lens wearers.

Granted 1976ExpiredExpired 1995Owned by Burton Parsons and Co IncInvented by Billy F. Rankin

Original patent title: “Polystyrene sulfonate containing opthalmic solutions

Plain-English explanation by SahiLast reviewed · June 15, 2026

A 1975 patent for an eye drop solution that uses a specific polymer to lubricate and cushion the eye, especially for contact lens wearers. Granted to Burton Parsons and Co Inc in 1976 with 9 claims and 37 forward citations.

Key facts

Patent numberUS 3987163
StatusExpired
FieldBiotech & Medicine
AssigneeBurton Parsons and Co Inc
InventorBilly F. Rankin
Filed1975
Granted1976
Claims9
Times cited37
LitigationNone on record
Value · $27K$86KMinimal

Coverage

What does this patent actually cover?

The patent describes an eye drop solution containing polystyrene sulfonate, a polymer with a high molecular weight between 75,000 and 10,000,000. This polymer acts as a synthetic mucus layer to lubricate and cushion the eye, which is particularly useful for people experiencing irritation from hard or gel-type contact lenses. The solution is formulated to be either acidic or buffered to a pH between 7.4 and 8.2 to remain compatible with human eye tissue. It can also include additional agents like cellulose derivatives or surfactants to improve the solution's performance as a wetting or cleaning agent.

The gap

What does this patent NOT cover?

  • Does not cover eye solutions that do not contain a styrene sulfonate polymer.
  • Does not cover solutions where the polymer molecular weight falls outside the 75,000 to 10,000,000 range.
  • Does not cover treatments for eye conditions that do not benefit from a synthetic mucus layer or lubrication.
  • Does not cover the manufacturing process of the contact lenses themselves.

These exclusions are unique to PatentBrief — derived from the actual claim language, not patent-office boilerplate.

What made this novel

The invention uses a high-molecular-weight polymer to mimic the natural lubricating properties of mucus, providing a cushioning effect that remains stable on the eye surface.

Polystyrene sulfonate containi…(Primary claim)biotechpharmaceutical

Schematic visualization of the patent's claim structure. Hand-drawn diagrams in progress for each landmark patent.

Where you've seen this

Real-world examples

01

Lubricating eye drops for contact lens wearers

02

Artificial tear solutions

03

Ophthalmic drug delivery vehicles

Why it matters

The bigger picture

This patent addressed the growing discomfort associated with early hard and soft contact lenses in the 1970s. By creating a synthetic mucus layer, it provided a way to manage dry eye symptoms and lens-related trauma, influencing the development of modern artificial tear formulations.

Filed

May 1, 1975

Granted

October 19, 1976

Market context

Who's building on this

Companies in this space

Major pharmaceutical companies specializing in ophthalmology, such as Alcon and Bausch + Lomb, have continued to refine the use of polymers and buffers in eye care products. These companies build on the foundational concept of using viscosity-modifying agents to improve ocular comfort.

Market impact

This patent contributed to the commercial viability of early contact lenses by providing a necessary comfort solution. It helped establish the category of lubricating eye drops as an essential companion product for the growing contact lens market in the late 20th century.

Claim 1 — Plain English

What this patent covers

The patent describes an eye drop solution containing polystyrene sulfonate, a polymer with a high molecular weight between 75,000 and 10,000,000. This polymer acts as a synthetic mucus layer to lubricate and cushion the eye, which is particularly useful for people experiencing irritation from hard or gel-type contact lenses. The solution is formulated to be either acidic or buffered to a pH between 7.4 and 8.2 to remain compatible with human eye tissue. It can also include additional agents like cellulose derivatives or surfactants to improve the solution's performance as a wetting or cleaning agent.

The clever bit

The invention uses a high-molecular-weight polymer to mimic the natural lubricating properties of mucus, providing a cushioning effect that remains stable on the eye surface.

What it does not cover

  • Does not cover eye solutions that do not contain a styrene sulfonate polymer.
  • Does not cover solutions where the polymer molecular weight falls outside the 75,000 to 10,000,000 range.
  • Does not cover treatments for eye conditions that do not benefit from a synthetic mucus layer or lubrication.
  • Does not cover the manufacturing process of the contact lenses themselves.

Patent timeline

Filing

Application submitted to the patent office

Publication

Application published, typically 18 months after filing

Grant

Patent officially issued

PatentBrief Score

Impact Score

Early stage

Citation count

32/40

Moderately cited

Claim breadth

6/20

Moderate scope

Recency

0/20

Older than 20 years

Assignee scale

0/20

Independent or smaller assigneeassigneeThe entity that owns the patent — usually the inventor's employer or a company.Read more →

PatentBrief Impact Score — based on citation count, claim breadth, recency, and assignee scale. Not a legal assessment.

Heuristic Value Estimate

What this patent might be worth

Minimal

$27K$86K

Midpoint $54K · expired or expiring · industry ×2.4

Adjust inputs →

Heuristic only — blends forward/backward citation counts, claim scope, time remaining, litigation history, and CPC-derived industry baseline. Real valuations need a professional appraisal.

The original legal language

Original claims

9 claims as filed with the patent office.

Concepts involved

ClaimPrior artNon-obviousnessNoveltySpecificationAssigneePatent term

Citations

Patent lineage

Cites earlier patents

5

earlier patents this invention cites as foundations

View prior art →

Cited by later patents

37

later patents that build on this invention

View patents →

Cite this patent

Rankin, B. F. (1976). How Polystyrene Sulfonate Helps Treat Dry Eye Symptoms (U.S. Patent No. 3,987,163). U.S. Patent and Trademark Office. https://patentbrief.org/patent/us/3987163/indomethacin

Auto-generated from the patent record. Double-check author order and the issue date against the official USPTO document before submitting.

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Common Questions

Frequently Asked Questions

What does How Polystyrene Sulfonate Helps Treat Dry Eye Symptoms cover?

A 1975 patent for an eye drop solution that uses a specific polymer to lubricate and cushion the eye, especially for contact lens wearers.

Who owns patent US 3987163?

Burton Parsons and Co Inc owns this patent, granted in 1976.

When does this patent expire?

This patent has expired and is now in the public domain — anyone can use the invention freely.

What is patent US 3987163 cited by?

This patent has been cited by 37 later patents that build on its ideas.

What problem does this patent solve?

This patent addressed the growing discomfort associated with early hard and soft contact lenses in the 1970s. By creating a synthetic mucus layer, it provided a way to manage dry eye symptoms and lens-related trauma, influencing the development of modern artificial tear formulations.

What does this patent NOT cover?

Does not cover eye solutions that do not contain a styrene sulfonate polymer.

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Last reviewed: June 15, 2026 · PatentBrief is not a law firm and this is not legal advice.