Whole genome sgrna library constructing system and application thereof
Provided are a system for constructing a genome-wide sgRNA library and a use thereof. The system includes an input module, an sgRNA design module and an sgRNA filtering module. By constructing three modules in the system…
Original patent title: “Whole genome sgrna library constructing system and application thereof”
Provided are a system for constructing a genome-wide sgRNA library and a use thereof. The system includes an input module, an sgRNA design module and an sgRNA filtering module. By constructing three modules in the system…. Owned by Genewiz Suzhou with 11 claims and 1 forward citation, and it is expected to expire in 2038.
Coverage
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Provided are a system for constructing a genome-wide sgRNA library and a use thereof. The system includes an input module, an sgRNA design module and an sgRNA filtering module. By constructing three modules in the system, optimizing details and processes in the modules, and adopting multiple design criteria and screening principles, the genome-wide sgRNA library is finally constructed. The system and method are concise and efficient, and the obtained library has a high quality and good activity, and is convenient for applications in gene editing researches.
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Patent Abstract
Patent abstract
Provided are a system for constructing a genome-wide sgRNA library and a use thereof. The system includes an input module, an sgRNA design module and an sgRNA filtering module. By constructing three modules in the system, optimizing details and processes in the modules, and adopting multiple design criteria and screening principles, the genome-wide sgRNA library is finally constructed. The system and method are concise and efficient, and the obtained library has a high quality and good activity, and is convenient for applications in gene editing researches.
Patent timeline
Application submitted to the patent office
Patent enters public domain
PatentBrief Score
Impact Score
Early stage
Citation count
6/40
Early citations
Claim breadth
7/20
Moderate scope
Recency
0/20
Older than 20 years
Assignee scale
20/20
Major company or institution
PatentBrief Impact Score — based on citation count, claim breadth, recency, and assignee scale. Not a legal assessment.
Heuristic Value Estimate
What this patent might be worth
$60K – $192K
Midpoint $120K · 12.5 yr remaining · industry ×2.0
Heuristic only — blends forward/backward citation counts, claim scope, time remaining, litigation history, and CPC-derived industry baseline. Real valuations need a professional appraisal.
The original legal language
Original claims
11 claims as filed with the patent office.
Concepts involved
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Cite this patent
Zhao, W., Jin, L., Xu, F., Ge, Y., Duan, G., & Xu, P. Whole genome sgrna library constructing system and application thereof (U.S. Patent No. 20,230,187,025). U.S. Patent and Trademark Office. https://patentbrief.org/patent/us/20230187025/whole-genome-sgrna-library-constructing-system-and-application-thereof
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Who owns patent US 20230187025?
This patent is owned by Genewiz Suzhou.
When does this patent expire?
This patent is expected to expire on December 14, 2038, when the invention enters the public domain.
What is patent US 20230187025 cited by?
This patent has been cited by 1 later patents that build on its ideas.
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