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Method for the detection of a binding partner of a multispecific binder

Herein is reported a method for the detection of free antigen of a multispecific antibody in a sample, whereby the antigen to be detected can be specifically bound by a first binding site of the multispecific antibody, c…

ActiveExpires 2040Owned by Hoffmann La RocheInvented by Kay-Gunnar Stubenrauch, Uwe Wessels

Original patent title: “Method for the detection of a binding partner of a multispecific binder”

Plain-English explanation by SahiLast reviewed · October 29, 2026

Herein is reported a method for the detection of free antigen of a multispecific antibody in a sample, whereby the antigen to be detected can be specifically bound by a first binding site of the multispecific antibody, c…. Owned by Hoffmann La Roche with 13 claims, and it is expected to expire in 2040.

Coverage

What does this patent actually cover?

Herein is reported a method for the detection of free antigen of a multispecific antibody in a sample, whereby the antigen to be detected can be specifically bound by a first binding site of the multispecific antibody, comprising the step of incubating a sample comprising free antigen and multispecific antibody with an anti-idiotypic antibody, which specifically binds to a second binding specificity of the bispecific antibody, which is different from the first binding specificity, whereby the anti-idiotypic antibody is bound to a solid phase.

The gap

What does this patent NOT cover?

    These exclusions are unique to PatentBrief — derived from the actual claim language, not patent-office boilerplate.

    Key facts

    Patent numberUS 20210055304
    StatusActive
    FieldOther Fields
    AssigneeHoffmann La Roche
    InventorsKay-Gunnar Stubenrauch, Uwe Wessels
    Filed2020
    Expires2040
    Claims13
    Times cited0
    LitigationNone on record
    Value · $23K–$72KMinimal

    The Patent Drawing

    Representative patent drawing for Method for the detection of a binding partner of a multispecific binder (US 20210055304)
    Representative figure · US 20210055304All figures on Google Patents →
    Method for the detection of a …(Primary claim)

    Schematic visualization of the patent's claim structure. Hand-drawn diagrams in progress for each landmark patent.

    Patent Abstract

    Patent abstract

    Herein is reported a method for the detection of free antigen of a multispecific antibody in a sample, whereby the antigen to be detected can be specifically bound by a first binding site of the multispecific antibody, comprising the step of incubating a sample comprising free antigen and multispecific antibody with an anti-idiotypic antibody, which specifically binds to a second binding specificity of the bispecific antibody, which is different from the first binding specificity, whereby the anti-idiotypic antibody is bound to a solid phase.

    Patent timeline

    Filing

    Application submitted to the patent office

    Expiration

    Patent enters public domain

    PatentBrief Score

    Impact Score

    Limited data

    Citation count

    0/40

    No citations yet

    Claim breadth

    9/20

    Moderate scope

    Recency

    0/20

    Older than 20 years

    Assignee scale

    0/20

    Independent or smaller assigneeassigneeThe entity that owns the patent — usually the inventor's employer or a company.Read more →

    PatentBrief Impact Score — based on citation count, claim breadth, recency, and assignee scale. Not a legal assessment.

    Heuristic Value Estimate

    What this patent might be worth

    Minimal

    $23K – $72K

    Midpoint $45K · 13.8 yr remaining · industry ×1.5

    Adjust inputs →

    Heuristic only — blends forward/backward citation counts, claim scope, time remaining, litigation history, and CPC-derived industry baseline. Real valuations need a professional appraisal.

    Claim text not yet imported for this patent

    The original legal language

    Original claims

    13 claims as filed with the patent office.

    Concepts involved

    ClaimPrior artNon-obviousnessNoveltySpecificationAssigneePatent term

    Citations

    Patent lineage

    Cites earlier patents

    1

    earlier patents this invention cites as foundations

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    Cite this patent

    Stubenrauch, K., & Wessels, U. Method for the detection of a binding partner of a multispecific binder (U.S. Patent No. 20,210,055,304). U.S. Patent and Trademark Office. https://patentbrief.org/patent/us/20210055304/method-for-the-detection-of-a-binding-partner-of-a-multispecific-binder

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    Common Questions

    Frequently Asked Questions

    Who owns patent US 20210055304?

    This patent is owned by Hoffmann La Roche.

    When does this patent expire?

    This patent is expected to expire on July 31, 2040, when the invention enters the public domain.

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    Last reviewed: — · PatentBrief is not a law firm and this is not legal advice.