How Enzymes Help Turn Corn Into Ethanol More Efficiently
A process for making ethanol from starch by using specific enzymes to break down proteins, which helps the fermentation process run more smoothly.
Patent Number
US RE50567
Status
Active
Filing Date
February 7, 2006
Grant Date
September 2, 2025
Expiration
~February 2026 (estimated)
Claims
33
Assignee
Novozymes North America Inc
Inventors
Mads Torry Smith, John Ress, Kevin S. Wenger, Rikke Monica Festersen
Citations
0 forward · 11 backward
What it covers
This patent describes a method to improve the production of ethanol from starch-based materials like corn. It involves a specific sequence: first, liquefying starch using an alpha-amylase enzyme, then adding a protease enzyme to break down proteins in the mixture. By degrading these proteins before the saccharification step—where sugars are generated—the process becomes more efficient. Finally, the mixture is fermented by an organism to produce alcohol, which can then be distilled.
What it doesn't cover
- —Does not cover processes that omit the specific protease treatment step before saccharification.
- —Does not cover production of ethanol from non-starch sources like cellulose or sugar cane juice.
- —Does not cover fermentation processes that do not use alpha-amylase for initial liquefaction.
The clever bit
The innovation lies in the specific timing of the protease addition. By treating the liquefied mash with a protease after liquefaction but before saccharification, the process clears away protein obstacles that typically hinder the efficiency of the sugar-generating enzymes.
Why it matters
This technology is central to the fuel ethanol industry, which relies on maximizing yield from corn feedstocks. By optimizing the breakdown of proteins that would otherwise interfere with enzyme performance, this process allows plants to produce more fuel from the same amount of raw material, directly impacting the economics of renewable energy production.
Real-world examples
- 1.Industrial corn-to-ethanol biorefineries
- 2.Biofuel production facilities using starch-containing agricultural waste
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US RE50567 · 2026