Immunotheraphy using single chain polypeptide binding molecules
The invention pertains to a single polypeptide chain binding molecule which has binding specificity and affinity substantially similar to the binding specificity and affinity of the light and heavy chain aggregate variab
Patent Number
US 5455030
Status
Active
Filing Date
April 1, 1993
Grant Date
October 3, 1995
Expiration
~April 2013 (estimated)
Claims
16
Assignee
Enzon Labs Inc
Inventors
Robert C. Ladner, Robert E. Bird, Karl Hardman
Citations
440 forward · 28 backward
What it covers
The invention pertains to a single polypeptide chain binding molecule which has binding specificity and affinity substantially similar to the binding specificity and affinity of the light and heavy chain aggregate variable region of an antibody, to genetic sequences coding therefor, and to recombinant DNA methods of producing such molecule and uses for such molecule.
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