Robot Systems for Automated Cell Processing with Cartridges

This patent describes an automated system where a robot moves specialized cartridges containing cells between several different instruments, each performing specific cell processing steps.

What it covers

This patent outlines a system designed to automate the handling of cells for various processing operations. It includes multiple instruments, each set up to perform specific tasks on a cell-containing cartridge. A robot then moves these cartridges from one instrument to another. For example, a robot might pick up a cartridge from an instrument that washes cells, then move it to another instrument that sorts cells, and finally to a third instrument that prepares them for storage, all without human intervention.

What it doesn't cover

• —Does not cover cell processing systems that use only a single instrument, as it specifies a 'plurality of instruments'.
• —Does not cover systems where cell-containing cartridges are moved manually between instruments, requiring a 'robot capable of moving the cartridge'.
• —Does not cover processing cells directly in bulk containers or multi-well plates without the use of a 'cartridge'.
• —Does not cover systems where instruments are permanently fixed in a single, unchangeable sequence, as the instruments are 'each independently configured'.

The clever bit

The novelty lies in integrating a robot to manage the workflow between multiple, independently configurable instruments, allowing for flexible and automated sequencing of complex cell processing steps on individual cartridges.

Why it matters

Automating cell processing is crucial for consistency and efficiency in fields like cell therapy and drug discovery. By using a robot to move cartridges between instruments, this system can reduce human error, increase throughput, and ensure standardized conditions for delicate cell samples. This approach helps scale up complex biological workflows, making advanced therapies more accessible.

Real-world examples

• 1.Automated cell therapy manufacturing platforms
• 2.High-throughput drug screening systems
• 3.Automated cell culture and analysis workstations
• 4.Robotic laboratory automation solutions