David H. Gelfand

How to Make Many Copies of a DNA Piece with Heat

This patent describes the Polymerase Chain Reaction (PCR) method, a technique to make millions of copies of a specific DNA segment using a heat-resistant enzyme and repeated temperature changes.

How an Enzyme Helps Find Specific DNA in a Sample

This patent describes a method for detecting a specific DNA sequence in a sample by using a labeled DNA probe and an enzyme that cuts the probe, releasing detectable fragments.

Using Heat-Resistant Enzymes to Read DNA Sequences Faster

This patent describes using a heat-stable enzyme from a bacterium that lives in hot springs to make the process of reading DNA code much more reliable and efficient.