University of Pennsylvania Penn

How Modified RNA Tricks Cells Into Making Proteins Without Triggering Attacks

A breakthrough method for using modified RNA to deliver instructions to cells without causing the body to reject the treatment as a foreign invader.

How Genetically Modified T-Cells Fight CD19 Cancers

This patent describes how to create and use genetically modified human T cells that target and kill cancer cells expressing the CD19 protein, offering a new way to treat blood cancers.

How Genetically Modified T-Cells Attack Cancer

This patent describes how human T cells are genetically engineered to express a special receptor (CAR) that specifically targets and kills cancer cells, particularly those with the CD19 marker, offering a new way to treat cancer.

Using a Blood Marker to Predict Concussion Risk and Severity

This patent describes a method to diagnose and predict long-term issues from mild traumatic brain injury, like concussions, by measuring a specific protein fragment called SNTF in a blood sample.