{
  "patent_number": "US 8882665",
  "country": "US",
  "title": "How Continuous Glucose Monitors Estimate Blood Sugar Levels Accurately",
  "original_title": "Method and/or system for multicompartment analyte monitoring",
  "summary": "This patent describes a method for accurately estimating blood glucose levels by accounting for the natural delay in glucose moving between interstitial fluid and blood, using sensor data and its rate of change.",
  "what_it_does": "The patent describes a system and method (Claim 1, 13) for monitoring a substance, called an \"analyte,\" in the body. It specifically focuses on estimating the analyte's concentration in a \"first physiological compartment\" (like blood plasma, Claim 2) by taking measurements from a \"second physiological compartment\" (like interstitial fluid, Claim 2). The system \"models a latency\" (a delay) in how the analyte moves between these two compartments and then \"compensates for the latency\" when calculating the final estimate. For example, if a continuous glucose monitor (CGM) measures glucose in the interstitial fluid, a processor predicts the blood glucose level, even though there's a natural time lag for glucose to move. This compensation uses not just the current sensor reading, but also the \"estimated rate of change\" of that sensor signal (Claim 1) to improve accuracy.",
  "what_it_does_not_cover": [
    "Does not cover systems that measure analyte levels directly in the first physiological compartment (e.g., a finger-prick blood glucose meter).",
    "Does not cover methods that estimate analyte concentration without accounting for the latency between two compartments.",
    "Does not cover systems that only use a single measurement value without considering the rate of change of the sensor signal for latency modeling.",
    "Does not cover methods where the \"first physiological compartment\" is not blood plasma or the \"second physiological compartment\" is not interstitial fluid, if glucose is the analyte (Claim 2 specifies this common scenario)."
  ],
  "filed": "2011-10-26",
  "granted": "2014-11-11",
  "expires": "2031-10-26",
  "status": "active",
  "holder": "Medtronic Minimed",
  "holder_url": "https://patentbrief.org/company/medtronic-minimed",
  "inventors": [
    {
      "name": "Xiaolong Li",
      "url": "https://patentbrief.org/inventor/xiaolong-li"
    },
    {
      "name": "Ning Yang",
      "url": "https://patentbrief.org/inventor/ning-yang"
    },
    {
      "name": "Keith Nogueira",
      "url": "https://patentbrief.org/inventor/keith-nogueira"
    },
    {
      "name": "Rebecca K. Gottlieb",
      "url": "https://patentbrief.org/inventor/rebecca-k-gottlieb"
    },
    {
      "name": "Bradley Liang",
      "url": "https://patentbrief.org/inventor/bradley-liang"
    }
  ],
  "times_cited": 9,
  "tags": [
    "biotech",
    "medical_devices",
    "software",
    "consumer_electronics"
  ],
  "abstract": "Subject matter disclosed herein relates to monitoring and/or controlling levels of an analyte in bodily fluid. In particular, estimation of a concentration of the analyte in a first physiological compartment based upon observations of a concentration of the analyte in a second physiological compartment may account for a latency in transporting the analyte between the first and second physiological compartments.",
  "url": "https://patentbrief.org/patent/us/8882665/method-andor-system-for-multicompartment-analyte-monitoring-8882665",
  "markdown_url": "https://patentbrief.org/patent/us/8882665/method-andor-system-for-multicompartment-analyte-monitoring-8882665/md",
  "google_patents_url": "https://patents.google.com/patent/US8882665",
  "relatedPatents": []
}