{
  "patent_number": "US 8053198",
  "country": "US",
  "title": "Method for Diagnosing Ovarian Cancer Using Biomarkers",
  "original_title": "Diagnostic methods",
  "summary": "This patent describes a method to diagnose ovarian cancer by measuring specific protein levels in a patient's blood sample and comparing them to normal levels.",
  "what_it_does": "This patent outlines a diagnostic method for identifying ovarian cancer. It involves measuring the level of a specific protein, called Flt-1, in a patient's blood sample (serum or plasma). This measured level is then compared to the normal level of Flt-1 found in healthy individuals. If the patient's Flt-1 level is significantly higher than normal (specifically, more than one standard deviation above the normal level), it suggests the presence of ovarian cancer. The method can also include measuring other biomarkers like CA125 or IL-6, and using these additional measurements to help confirm the diagnosis. The entire process can be performed on a single blood sample, potentially within a single assay chamber.",
  "what_it_does_not_cover": [
    "Diagnosing any cancer other than ovarian cancer.",
    "Diagnosing ovarian cancer using only symptoms or imaging, without measuring biomarker levels.",
    "Using biomarkers other than Flt-1 as the sole indicator for diagnosing ovarian cancer.",
    "Methods that do not compare patient sample levels to a normal control sample.",
    "Diagnosing ovarian cancer based on levels that are not statistically significant deviations (e.g., less than one standard deviation above normal)."
  ],
  "filed": "2008-09-12",
  "granted": "2011-11-08",
  "expires": "2028-09-12",
  "status": "active",
  "holder": "Meso Scale Technologies",
  "holder_url": "https://patentbrief.org/company/meso-scale-technologies",
  "inventors": [
    {
      "name": "Martin Stengelin",
      "url": "https://patentbrief.org/inventor/martin-stengelin"
    },
    {
      "name": "Anu Mathew",
      "url": "https://patentbrief.org/inventor/anu-mathew"
    },
    {
      "name": "Eli Glezer",
      "url": "https://patentbrief.org/inventor/eli-glezer"
    }
  ],
  "times_cited": 0,
  "tags": [
    "biotech",
    "pharmaceutical",
    "medical_devices"
  ],
  "abstract": "The present invention relates to methods of diagnosing cancerous conditions in a patient, as well as methods of monitoring the progression of a cancerous condition and/or methods of monitoring a treatment protocol of a therapeutic agent or a chemotherapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.",
  "url": "https://patentbrief.org/patent/us/8053198/diagnostic-methods",
  "markdown_url": "https://patentbrief.org/patent/us/8053198/diagnostic-methods/md",
  "google_patents_url": "https://patents.google.com/patent/US8053198",
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}