{
  "patent_number": "US 2442141",
  "country": "US",
  "title": "How Andrew Moyer Learned to Mass-Produce Penicillin",
  "original_title": "Method for production of penicillin",
  "summary": "This 1948 patent details a method for growing the mold Penicillium in large vats using a corn steep liquor medium, which enabled the mass production of life-saving antibiotics.",
  "what_it_does": "The patent describes a method for increasing the yield of penicillin by using a specific culture medium containing corn steep liquor and lactose. By submerged fermentation in aerated tanks, the mold Penicillium chrysogenum produces significantly higher concentrations of the antibiotic than previous surface-growth methods. This process allowed the transition from slow, small-scale laboratory production to industrial-scale manufacturing.",
  "what_it_does_not_cover": [
    "Does not cover the discovery of penicillin itself",
    "Does not cover the medical application or dosage of penicillin",
    "Does not cover synthetic methods for creating penicillin-like compounds"
  ],
  "filed": "1945-05-11",
  "granted": "1948-05-25",
  "expires": null,
  "status": "active",
  "holder": "US Department of Agriculture USDA",
  "holder_url": "https://patentbrief.org/company/us-department-of-agriculture-usda",
  "inventors": [
    {
      "name": "Andrew J Moyer",
      "url": "https://patentbrief.org/inventor/andrew-j-moyer"
    }
  ],
  "times_cited": 13,
  "tags": [
    "biotech",
    "pharmaceutical"
  ],
  "abstract": null,
  "url": "https://patentbrief.org/patent/us/2442141/vitamin-b12-isolation",
  "markdown_url": "https://patentbrief.org/patent/us/2442141/vitamin-b12-isolation/md",
  "google_patents_url": "https://patents.google.com/patent/US2442141",
  "relatedPatents": []
}