{
  "patent_number": "US 20230176052",
  "country": "US",
  "title": "A New, More Accurate Test for 'Walking Pneumonia' Bacteria",
  "original_title": "Mycoplasma pneumoniae immunoassay method and immunoassay instrument",
  "summary": "This patent describes a new method and instrument for detecting *Mycoplasma pneumoniae*, the bacteria causing 'walking pneumonia,' using a special antibody that binds strongly to two specific proteins from the germ.",
  "what_it_does": "This patent describes an immunoassay method to detect *Mycoplasma pneumoniae* by using a unique monoclonal antibody. This antibody is special because it specifically reacts with two proteins from the bacteria, P1 protein and P30 protein (Claim 1). Crucially, this antibody also specifically recognizes a small part of a protein, called a peptide, that contains the amino acid sequence PPQPG (Claim 1). The method involves an 'antigen-antibody reaction' where the antibody binds to these bacterial proteins if they are present in a sample. The patent also covers instruments, like an 'immunochromatographic strip' (Claim 7), which is a type of rapid test strip, that uses this antibody. For example, a doctor could use a test strip coated with this antibody to quickly check a patient's sample for *Mycoplasma pneumoniae* proteins.",
  "what_it_does_not_cover": [
    "Does not cover immunoassay methods that do not use a monoclonal antibody specifically reacting with *both* P1 and P30 proteins of *Mycoplasma pneumoniae* (Claim 1).",
    "Does not cover antibodies that do not specifically react with a peptide containing the amino acid sequence PPQPG (Claim 1).",
    "Does not cover methods for detecting other types of bacteria or viruses, only *Mycoplasma pneumoniae* (Claim 1).",
    "Does not cover diagnostic methods that do not rely on an antigen-antibody reaction (Claim 1).",
    "Does not cover antibodies that only react with P1 protein or only with P30 protein, but not both (Claim 1)."
  ],
  "filed": "2021-04-06",
  "granted": null,
  "expires": "2041-04-06",
  "status": "active",
  "holder": "Denka Co",
  "holder_url": "https://patentbrief.org/company/denka-co",
  "inventors": [
    {
      "name": "Tomomi TAKANO",
      "url": "https://patentbrief.org/inventor/tomomi-takano"
    },
    {
      "name": "Risa Kohiyama",
      "url": "https://patentbrief.org/inventor/risa-kohiyama"
    },
    {
      "name": "Takashi Miyazawa",
      "url": "https://patentbrief.org/inventor/takashi-miyazawa"
    }
  ],
  "times_cited": 0,
  "tags": [
    "biotech",
    "pharmaceutical",
    "medical_devices",
    "diagnostics"
  ],
  "abstract": "An immunoassay utilizing a monoclonal antibody which specifically reacts with both of P1 protein and P30 protein of Mycoplasma pneumoniae, which monoclonal antibody has a higher affinity with P1 protein and P30 protein of Mycoplasma pneumoniae than the known monoclonal antibodies, is disclosed. The immunoassay utilizes an antigen-antibody reaction between a monoclonal antibody which specifically reacts with P1 protein and P30 protein of Mycoplasma pneumoniae and which specifically reacts with a peptide containing an amino acid sequence composed of PPQPG or antigen-binding fragment thereof, and P1 protein and P30 protein derived from Mycoplasma pneumoniae.",
  "url": "https://patentbrief.org/patent/us/20230176052/mycoplasma-pneumoniae-immunoassay-method-and-immunoassay-instrument",
  "markdown_url": "https://patentbrief.org/patent/us/20230176052/mycoplasma-pneumoniae-immunoassay-method-and-immunoassay-instrument/md",
  "google_patents_url": "https://patents.google.com/patent/US20230176052",
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}