{
  "patent_number": "US 12735721",
  "country": "US",
  "title": "Engineered AAV Vectors for Targeted Gene Delivery to Specific Body Parts",
  "original_title": "Engineered adeno-associated (AAV) vectors for transgene expression",
  "summary": "This patent describes specially designed adeno-associated virus (AAV) vectors that can deliver new genetic material to specific tissues in the body, such as the brain, heart, or retina, to treat diseases.",
  "what_it_does": "This patent relates to engineered adeno-associated (AAV) vectors. These vectors are modified viruses used to carry new genes into cells. The engineering allows these AAV vectors to specifically deliver genetic material, called transgenes, to particular parts of the body. For example, the patent mentions targeting the central nervous system (CNS), peripheral nervous system (PNS), inner ear, heart, or retina. This means the vectors are designed to express a desired gene primarily in cells within these specific organs or tissues. The patent also describes methods for finding new engineered AAV vectors that can deliver genes to desired cell types.",
  "what_it_does_not_cover": [
    "Does not cover gene delivery methods that use viral vectors other than adeno-associated viruses (AAV).",
    "Does not cover AAV vectors that are not specifically engineered for targeted transgene expression.",
    "Does not cover AAV vectors used for purposes other than delivering and expressing a transgene, such as direct gene editing without expression.",
    "Does not cover delivery of genetic material to tissues or organs not mentioned in the abstract, unless they fall under the broad categories of CNS or PNS.",
    "Does not cover general, non-engineered AAV vectors that lack specificity for particular cell types or tissues."
  ],
  "filed": "2020-03-30",
  "granted": "2026-09-15",
  "expires": null,
  "status": "active",
  "holder": null,
  "holder_url": null,
  "inventors": [],
  "times_cited": 0,
  "tags": [
    "biotech",
    "pharmaceutical",
    "gene_editing",
    "healthcare"
  ],
  "abstract": "Engineered AAV vectors for transgene expression, e.g., in the CNS, PNS, inner ear, heart, or retina, and methods of use thereof. Also provided are methods for discovering new engineered AAV vectors that mediate transgene expression in desired cell types.",
  "url": "https://patentbrief.org/patent/us/12735721/engineered-adeno-associated-aav-vectors-for-transgene-expression",
  "markdown_url": "https://patentbrief.org/patent/us/12735721/engineered-adeno-associated-aav-vectors-for-transgene-expression/md",
  "google_patents_url": "https://patents.google.com/patent/US12735721",
  "relatedPatents": []
}