{
  "patent_number": "US 12735707",
  "country": "US",
  "title": "Blocking RUNX1 to Stop Eye Scarring and Cell Changes",
  "original_title": "RUNX1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition",
  "summary": "This patent describes using methods and substances to stop certain cells in the eye from growing too much or changing their type, which can cause serious eye conditions like scarring.",
  "what_it_does": "The patent describes ways to prevent or reduce the unwanted growth or movement of cells in the retina, which is the light-sensing part of the eye. It also aims to stop a process called 'epithelial to mesenchymal transition' (EMT) in eye cells, and potentially cells from other body parts. This involves using specific compositions and formulations to target these cellular activities. For instance, in conditions like proliferative vitreoretinopathy, where scar tissue forms in the eye, this invention could provide a treatment to slow down or stop the cells that cause this scarring from multiplying and spreading.",
  "what_it_does_not_cover": [
    "Does not cover treatments for eye conditions that do not involve the RUNX1 protein.",
    "Does not cover methods that increase, rather than reduce, cell growth or movement.",
    "Does not cover diagnostic tools for identifying proliferative vitreoretinopathy.",
    "Does not cover treatments for conditions where epithelial to mesenchymal transition is beneficial.",
    "Does not cover therapies that do not involve specific compositions or formulations."
  ],
  "filed": "2023-07-12",
  "granted": "2026-09-15",
  "expires": null,
  "status": "active",
  "holder": null,
  "holder_url": null,
  "inventors": [],
  "times_cited": 0,
  "tags": [
    "biotech",
    "pharmaceutical",
    "medical",
    "cell_biology",
    "drug_discovery"
  ],
  "abstract": "The present subject matter provides compositions. formulations and methods for preventing or reducing proliferation or migration of retinal cells or epithelial to mesenchymal transition in ocular cells or cells from other tissues.",
  "url": "https://patentbrief.org/patent/us/12735707/runx1-inhibition-for-treatment-of-proliferative-vitreoretinopathy-and",
  "markdown_url": "https://patentbrief.org/patent/us/12735707/runx1-inhibition-for-treatment-of-proliferative-vitreoretinopathy-and/md",
  "google_patents_url": "https://patents.google.com/patent/US12735707",
  "relatedPatents": []
}