{
  "patent_number": "US 12735503",
  "country": "US",
  "title": "Using Antibodies and CAR-T Cells to Fight MUC1-C Expressing Cancers",
  "original_title": "Anti-MUC1-C antibodies and CAR-T structures",
  "summary": "This patent describes specific antibodies and engineered immune cells (CAR-T) designed to target and treat cancers that produce a particular protein called MUC1-C.",
  "what_it_does": "The patent discloses anti-MUC1-C antibodies, including a type referred to as UniAbs™, and CAR-T structures. These are designed to recognize and bind to the MUC1-C protein, which is found on certain cancer cells. The patent also covers methods for creating these antibodies and CAR-T structures, as well as pharmaceutical compositions containing them. The core purpose is to use these specialized biological tools to treat diseases, specifically cancers, that are characterized by the presence of MUC1-C. For example, a patient with a MUC1-C expressing tumor could potentially receive a therapy made from these CAR-T cells to help their immune system attack the cancer.",
  "what_it_does_not_cover": [
    "Does not cover therapies targeting cancer markers or proteins other than MUC1-C.",
    "Does not cover cancer treatments that do not involve antibodies or CAR-T structures.",
    "Does not cover methods for diagnosing MUC1-C expressing disorders, focusing only on treatment.",
    "Does not cover the use of non-antibody-based molecules or different types of cell therapies to target MUC1-C."
  ],
  "filed": "2022-02-28",
  "granted": "2026-09-15",
  "expires": null,
  "status": "active",
  "holder": null,
  "holder_url": null,
  "inventors": [],
  "times_cited": 0,
  "tags": [
    "biotech",
    "pharmaceutical",
    "gene_editing",
    "oncology"
  ],
  "abstract": "Anti-MUC1-C antibodies (e.g., UniAbs™) and CAR-T structures are disclosed, along with methods of making such antibodies and CAR-T structures, compositions, including pharmaceutical compositions, comprising such antibodies and CAR-T structures, and their use to treat disorders that are characterized by the expression of MUC1-C.",
  "url": "https://patentbrief.org/patent/us/12735503/anti-muc1-c-antibodies-and-car-t-structures",
  "markdown_url": "https://patentbrief.org/patent/us/12735503/anti-muc1-c-antibodies-and-car-t-structures/md",
  "google_patents_url": "https://patents.google.com/patent/US12735503",
  "relatedPatents": []
}