{
  "patent_number": "US 12734239",
  "country": "US",
  "title": "Universal Cells to Grow Cancer-Fighting Immune Cells",
  "original_title": "K562 universal antigen presenting cells and uses thereof",
  "summary": "This patent describes special 'universal' cells called K562 UAPCs that can help grow large numbers of immune cells to fight diseases like cancer.",
  "what_it_does": "The patent provides 'universal antigen presenting cells' (UAPCs) derived from K562 cells. These UAPCs are designed to stimulate and expand immune cells, such as T-cells, outside the body. By presenting specific signals, these UAPCs encourage immune cells to multiply rapidly. Once expanded, these larger quantities of immune cells can be used as a treatment, for example, to target and destroy cancer cells in a patient. The 'universal' aspect suggests these cells can be used for many different patients without needing specific genetic matching.",
  "what_it_does_not_cover": [
    "Does not cover antigen-presenting cells that require specific HLA matching for each patient, as the patent focuses on 'universal' cells.",
    "Does not cover methods of treating disease that do not involve expanding immune cells, as the core mechanism is immune cell proliferation.",
    "Does not cover immune cell expansion methods that do not use K562-derived universal antigen presenting cells.",
    "Does not cover the K562 cell line itself, but rather its specific modification and use as a universal antigen-presenting cell."
  ],
  "filed": "2019-02-21",
  "granted": "2026-09-15",
  "expires": null,
  "status": "active",
  "holder": null,
  "holder_url": null,
  "inventors": [],
  "times_cited": 0,
  "tags": [
    "biotech",
    "pharmaceutical",
    "cancer_therapy",
    "immunotherapy",
    "cell_therapy"
  ],
  "abstract": "Provided herein are universal antigen presenting cells. Also provided herein are methods of expanding immune cells using the UAPCs and methods for the treatment of a disease, such as cancer, using the expanded immune cells.",
  "url": "https://patentbrief.org/patent/us/12734239/k562-universal-antigen-presenting-cells-and-uses-thereof",
  "markdown_url": "https://patentbrief.org/patent/us/12734239/k562-universal-antigen-presenting-cells-and-uses-thereof/md",
  "google_patents_url": "https://patents.google.com/patent/US12734239",
  "relatedPatents": []
}