# How Tiny Particles Make CBD Easier to Absorb > This patent describes a special mix of ingredients that creates tiny, stable CBD particles, making it easier for the body to absorb the compound and improving how long it lasts in the body. - **Patent:** US 11260033 - **Original title:** Compositions for the delivery of therapeutic agents and methods of use and making thereof - **Owner:** Disruption Labs - **Granted:** 2022 - **Status:** Active - **Times cited:** 2 - **Field:** biotech, pharmaceutical, consumer_electronics, materials ## What it does This patent covers a lipid-based nanoparticle composition designed to deliver cannabidiol (CBD). The composition is an oil-in-water nanoemulsion, meaning tiny oil droplets containing CBD are evenly spread in water. It includes specific amounts of CBD (1-10%), phosphatidylcholine (2.5-15%), a sterol (0.5-5%), and a medium chain triglyceride (2.5-15%), with water making up 60-80% of the mix (Claim 1). The nanoparticles are very small, averaging 75 nm to 200 nm, which helps with absorption. A key feature is their stability: the nanoparticles change size by less than 10% when exposed to simulated stomach or intestinal fluids for at least an hour (Claim 1). This stability helps the CBD survive digestion and get into the bloodstream more effectively, potentially leading to faster absorption (Tmax less than 4.5 hours, Claim 3) and higher concentrations in the body (Cmax of at least 80 ng/ml after 15 mg/kg dose, Claim 13). For example, a person could take this composition orally, and the CBD would be absorbed more efficiently than other forms. ## What it does NOT cover - Does not cover CBD compositions that use traditional surfactants or emulsifiers other than phosphatidylcholine (Claim 1). - Does not cover compositions where the CBD, phosphatidylcholine, sterol, or medium chain triglyceride fall outside the specified weight percentages (Claim 1). - Does not cover nanoparticles that change size by more than 10% when exposed to simulated gastric or intestinal fluids (Claim 1). - Does not cover compositions where the average nanoparticle size is outside the 75 nm to 200 nm range (Claim 1). - Does not cover the delivery of therapeutic agents other than cannabidiol (CBD) using this specific composition (Claim 1). ## The clever bit The clever part is creating a highly stable, small-particle CBD nanoemulsion without relying on common synthetic surfactants. By using specific ratios of natural lipids like phosphatidylcholine and sterols, the composition achieves excellent stability in harsh digestive environments and enhances the body's ability to absorb CBD. ## Real-world examples 1. CBD oil tinctures designed for enhanced bioavailability 2. CBD-infused beverages 3. CBD capsules or softgels with improved absorption 4. Topical CBD creams or lotions using nanoemulsion technology ## Why it matters Many beneficial compounds, like CBD, are not easily absorbed by the body when taken orally. This patent provides a way to create a stable, highly absorbable form of CBD, which can improve its effectiveness for consumers. By ensuring the nanoparticles remain stable through the digestive system, it addresses a major challenge in delivering lipid-soluble compounds. This technology could lead to more reliable and potent CBD products, enhancing their therapeutic potential. ## Frequently asked questions ### What does How Tiny Particles Make CBD Easier to Absorb cover? This patent describes a special mix of ingredients that creates tiny, stable CBD particles, making it easier for the body to absorb the compound and improving how long it lasts in the body. ### Who owns patent US 11260033? Disruption Labs owns this patent, granted in 2022. ### When does this patent expire? This patent is expected to expire on March 24, 2041, when the invention enters the public domain. ### What is patent US 11260033 cited by? This patent has been cited by 2 later patents that build on its ideas. ### What problem does this patent solve? Many beneficial compounds, like CBD, are not easily absorbed by the body when taken orally. This patent provides a way to create a stable, highly absorbable form of CBD, which can improve its effectiveness for consumers. By ensuring the nanoparticles remain stable through the digestive system, it addresses a major challenge in delivering lipid-soluble compounds. This technology could lead to more reliable and potent CBD products, enhancing their therapeutic potential. ### What does this patent NOT cover? Does not cover CBD compositions that use traditional surfactants or emulsifiers other than phosphatidylcholine (Claim 1). **Full plain-English explainer:** https://patentbrief.org/patent/us/11260033/compositions-for-the-delivery-of-therapeutic-agents-and-methods-of-use-and-makin **Original patent:** https://patents.google.com/patent/US11260033 --- _Source: PatentBrief — https://patentbrief.org. Patent facts are from public records; the plain-English explanation is PatentBrief's._ ## Related patents Semantically similar inventions in the PatentBrief corpus: - [Tiny Lipid Balls for Precise, Better-Absorbed Cannabinoid Medicine](https://patentbrief.org/patent/us/20220304938/lipid-nanoparticle-compositions-and-methods-as-carriers-of-cannabinoids-in-stand) — This patent describes a drug delivery system using tiny lipid nanoparticles to encapsulate cannabinoids, making them easier for the body to absorb and allowing for precise, smaller doses. - [How to Build Tiny Lipid Carriers for Delivering Nutrients](https://patentbrief.org/patent/us/9925149/nanoparticle-compositions-and-methods-as-carriers-of-nutraceutical-factors-acros) — A method for creating tiny, 20-60 nanometer lipid-based particles designed to carry vitamins and nutrients into the human body more effectively. - [How to Make Hard-to-Absorb Medicines Easier for the Body to Use](https://patentbrief.org/patent/us/5002952/duragesic-fentanyl-patch) — A method for mixing specific chemical compounds with surfactants to help the body absorb them more effectively. - [Targeting Drugs to Specific Body Tissues Using ApoE3-Coated Nanoparticles](https://patentbrief.org/patent/us/20190307892/targeted-drug-delivery-and-therapeutic-methods-using-apo-e-modified-lipid-nanopa) — This patent describes a method to deliver drugs or diagnostic agents precisely to target cells or tissues, including the brain, by packaging them inside tiny fat particles (lipid nanoparticles) coated with a special protein called ApoE3. - [How Special Nanoparticles Deliver Cancer Drugs Directly to Tumors](https://patentbrief.org/patent/us/20190046446/apo-e-modified-lipid-nanoparticles-for-drug-delivery-to-targeted-tissues-and-the) — This patent describes tiny fat-based particles, called lipid nanoparticles, designed to carry cancer drugs directly to tumor cells using a special protein (ApoE3) on their surface, avoiding a common, potentially problematic ingredient.