{
  "patent_number": "US 10751416",
  "country": "US",
  "title": "Using Antibodies to Block IL-26 for Treating Inflammatory Diseases",
  "original_title": "IL-26 inhibitors",
  "summary": "A patent for specific antibodies that block the protein IL-26 to help treat inflammatory conditions like psoriasis and Crohn's disease.",
  "what_it_does": "This patent describes a specific monoclonal antibody designed to bind to and neutralize a protein called Interleukin-26 (IL-26). IL-26 is a signaling molecule that can trigger inflammation in the body. By using these antibodies to block IL-26, the treatment aims to stop the inflammatory response, specifically by preventing IL-26 from causing damage independently of its usual receptor. The patent details the exact amino acid sequences (the building blocks of the antibody) required for this specific binding, ensuring the antibody targets IL-26 effectively. This could be used in patients to reduce symptoms of inflammatory diseases, such as skin thickening in psoriasis or the overproduction of other inflammatory markers like IL-6 and TNF.",
  "what_it_does_not_cover": [
    "Does not cover any antibody that binds to IL-26 using different amino acid sequences than those specified in the claims.",
    "Does not cover treatments that use small molecule drugs instead of monoclonal antibodies or their fragments.",
    "Does not cover antibodies that bind to IL-26 but fail to inhibit its receptor-independent inflammatory function.",
    "Does not cover general methods of treating inflammation that do not involve the specific IL-26 inhibition described."
  ],
  "filed": "2016-07-13",
  "granted": "2020-08-25",
  "expires": null,
  "status": "active",
  "holder": "Centre Hospitalier Universitaire Vaudois CHUV",
  "holder_url": "https://patentbrief.org/company/centre-hospitalier-universitaire-vaudois-chuv",
  "inventors": [
    {
      "name": "Jeremy DI DOMIZIO",
      "url": "https://patentbrief.org/inventor/jeremy-di-domizio"
    },
    {
      "name": "Michel Gilliet",
      "url": "https://patentbrief.org/inventor/michel-gilliet"
    },
    {
      "name": "Stephan MELLER",
      "url": "https://patentbrief.org/inventor/stephan-meller"
    }
  ],
  "times_cited": 1,
  "tags": [
    "biotech",
    "pharmaceutical"
  ],
  "abstract": "The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with interleukin 26 (IL-26), including inflammatory diseases, such as psoriasis and/or bacterial infections.",
  "url": "https://patentbrief.org/patent/us/10751416/tagrisso-osimertinib",
  "markdown_url": "https://patentbrief.org/patent/us/10751416/tagrisso-osimertinib/md",
  "google_patents_url": "https://patents.google.com/patent/US10751416",
  "relatedPatents": []
}