{
  "patent_number": "US 10028963",
  "country": "US",
  "title": "How to Treat Severe Lung Infections Using Ceftolozane and Tazobactam",
  "original_title": "Methods for treating intrapulmonary infections",
  "summary": "A medical treatment method for severe, hospital-acquired pneumonia using a specific, recurring intravenous dose of the antibiotic combination ceftolozane and tazobactam.",
  "what_it_does": "The patent outlines a specific medical regimen for treating pneumonia, particularly infections acquired in hospital settings or via ventilators. It requires the intravenous administration of 2.0 grams of the antibiotic ceftolozane, combined with tazobactam, every 8 hours. The claims specify that this infusion should last for 60 minutes to be effective against common, stubborn pathogens like Pseudomonas aeruginosa, E. coli, and K. pneumoniae.",
  "what_it_does_not_cover": [
    "Does not cover oral administration of these antibiotics.",
    "Does not cover dosages other than the specified 2.0 grams of ceftolozane.",
    "Does not cover treatment regimens administered at intervals other than every 8 hours.",
    "Does not cover the chemical synthesis of the drugs themselves."
  ],
  "filed": "2017-06-21",
  "granted": "2018-07-24",
  "expires": null,
  "status": "active",
  "holder": "Merck Sharp and Dohme LLC",
  "holder_url": "https://patentbrief.org/company/merck-sharp-and-dohme-llc",
  "inventors": [
    {
      "name": "Tara Parsons",
      "url": "https://patentbrief.org/inventor/tara-parsons"
    },
    {
      "name": "Obiamiwe C. Umeh",
      "url": "https://patentbrief.org/inventor/obiamiwe-c-umeh"
    },
    {
      "name": "Gurudatt A. Chandorkar",
      "url": "https://patentbrief.org/inventor/gurudatt-a-chandorkar"
    },
    {
      "name": "Jennifer A. Huntington",
      "url": "https://patentbrief.org/inventor/jennifer-a-huntington"
    }
  ],
  "times_cited": 0,
  "tags": [
    "biotech",
    "pharmaceutical"
  ],
  "abstract": "This disclosure relates to the treatment of intrapulmonary bacterial infections, including treatment of nosocomial pneumonia lung infections with pharmaceutical compositions containing the cephalosporin ceftolozane.",
  "url": "https://patentbrief.org/patent/us/10028963/biktarvy-bictegravir-taf-ftc",
  "markdown_url": "https://patentbrief.org/patent/us/10028963/biktarvy-bictegravir-taf-ftc/md",
  "google_patents_url": "https://patents.google.com/patent/US10028963",
  "relatedPatents": []
}