# David H. Gelfand — Patents explained on PatentBrief

David H. Gelfand has 3 landmark patents explained in plain English on PatentBrief.

- [How an Enzyme Helps Find Specific DNA in a Sample](https://patentbrief.org/patent/us/5210015/hcv-pcr-detection) — granted 1993
  This patent describes a method for detecting a specific DNA sequence in a sample by using a labeled DNA probe and an enzyme that cuts the probe, releasing detectable fragments.
- [Using Heat-Resistant Enzymes to Read DNA Sequences Faster](https://patentbrief.org/patent/us/5075216/modified-taq-polymerase) — granted 1991
  This patent describes using a heat-stable enzyme from a bacterium that lives in hot springs to make the process of reading DNA code much more reliable and efficient.
- [How to Make Many Copies of a DNA Piece with Heat](https://patentbrief.org/patent/us/4965188/taq-polymerase-for-pcr) — granted 1990
  This patent describes the Polymerase Chain Reaction (PCR) method, a technique to make millions of copies of a specific DNA segment using a heat-resistant enzyme and repeated temperature changes.

**Full profile:** https://patentbrief.org/inventor/david-h-gelfand

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_Source: PatentBrief — https://patentbrief.org. Plain-English explanations of US patents._