# University of Pennsylvania Penn — Patents explained on PatentBrief

University of Pennsylvania Penn has 4 landmark patents explained in plain English on PatentBrief.

- [Using a Blood Marker to Predict Concussion Risk and Severity](https://patentbrief.org/patent/us/12085565/sntf-is-a-blood-biomarker-for-the-diagnosis-and-prognosis-of-sports-related-conc) — granted 2024
  This patent describes a method to diagnose and predict long-term issues from mild traumatic brain injury, like concussions, by measuring a specific protein fragment called SNTF in a blood sample.
- [How Genetically Modified T-Cells Fight CD19 Cancers](https://patentbrief.org/patent/us/9481728/compositions-and-methods-for-treatment-of-cancer) — granted 2016
  This patent describes how to create and use genetically modified human T cells that target and kill cancer cells expressing the CD19 protein, offering a new way to treat blood cancers.
- [How Genetically Modified T-Cells Attack Cancer](https://patentbrief.org/patent/us/9328156/use-of-chimeric-antigen-receptor-modified-t-cells-to-treat-cancer) — granted 2016
  This patent describes how human T cells are genetically engineered to express a special receptor (CAR) that specifically targets and kills cancer cells, particularly those with the CD19 marker, offering a new way to treat cancer.
- [How Modified RNA Tricks Cells Into Making Proteins Without Triggering Attacks](https://patentbrief.org/patent/us/8278036/rna-containing-modified-nucleosides-and-methods-of-use-thereof) — granted 2012
  A breakthrough method for using modified RNA to deliver instructions to cells without causing the body to reject the treatment as a foreign invader.

**Full profile:** https://patentbrief.org/company/university-of-pennsylvania-penn

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_Source: PatentBrief — https://patentbrief.org. Plain-English explanations of US patents._