Massachusetts Institute of Technology — New Patents | PatentBrief https://patentbrief.org/company/massachusetts-institute-of-technology Plain-English explanations of patents assigned to Massachusetts Institute of Technology, newest first. en-us Sun, 12 Jul 2026 09:21:50 GMT Highly Efficient Bacterial Gene Editing Using Guide RNA and Reverse Transcriptase https://patentbrief.org/patent/us/20180127759/dynamic-genome-engineering This patent describes a system for precisely editing the DNA of bacterial cells with very high success rates, using a combination of guide RNA, reverse transcriptase, and specific DNA sequences. Sat, 27 Jun 2026 10:27:35 GMT https://patentbrief.org/patent/us/20180127759/dynamic-genome-engineering How Special Molecules Boost Cancer-Fighting CAR-T Cells https://patentbrief.org/patent/us/20240082373/compositions-for-chimeric-antigen-receptor-t-cell-therapy-and-uses-thereof This patent describes special molecules made of a CAR-T cell activator attached to a fat-like part, designed to make cancer-fighting CAR-T cells grow and work better inside a patient. Thu, 02 Jul 2026 10:57:44 GMT https://patentbrief.org/patent/us/20240082373/compositions-for-chimeric-antigen-receptor-t-cell-therapy-and-uses-thereof Delivering Large Gene Editing Tools into Cells with Hybrid Virus-Lipid Packages https://patentbrief.org/patent/us/12350368/delivery-of-large-payloads This patent describes a sophisticated delivery system that combines parts of a virus with a fat bubble (liposome) to efficiently transport large molecules, like CRISPR gene-editing components, into specific cells. Tue, 08 Jul 2025 00:00:00 GMT https://patentbrief.org/patent/us/12350368/delivery-of-large-payloads How to Make Animals That Can Turn On CRISPR Gene Editing https://patentbrief.org/patent/us/12252707/delivery-engineering-and-optimization-of-systems-methods-and-compositions-for-se This patent describes creating genetically modified non-human animals, like mice, where a key CRISPR gene-editing protein (Cas9) can be turned on only in specific cells or at specific times using a special genetic switch. Tue, 18 Mar 2025 00:00:00 GMT https://patentbrief.org/patent/us/12252707/delivery-engineering-and-optimization-of-systems-methods-and-compositions-for-se How to Edit Genes in Human Cells Using an Engineered CRISPR System https://patentbrief.org/patent/us/8697359/crispr-gene-editing This patent describes an engineered CRISPR-Cas9 system for precisely cutting DNA in eukaryotic cells to change how genes work, opening the door for gene editing in complex organisms. Tue, 15 Apr 2014 00:00:00 GMT https://patentbrief.org/patent/us/8697359/crispr-gene-editing Tiny Capsules for Electronic Paper Displays https://patentbrief.org/patent/us/5961804/e-ink-electronic-paper-display MIT's 1999 patent on a special ink made of tiny capsules that can change color when an electric field is applied, forming the basis for early e-readers. Tue, 05 Oct 1999 00:00:00 GMT https://patentbrief.org/patent/us/5961804/e-ink-electronic-paper-display How RSA Public-Key Encryption Keeps Digital Messages Secret https://patentbrief.org/patent/us/4405829/rsa-encryption This patent describes the foundational RSA algorithm, a method for securely sending messages where anyone can encrypt a message using a public key, but only the intended recipient can decrypt it using a secret private key. Tue, 20 Sep 1983 00:00:00 GMT https://patentbrief.org/patent/us/4405829/rsa-encryption