# Hoffmann La Roche Inc — Patents explained on PatentBrief

Hoffmann La Roche Inc has 3 landmark patents explained in plain English on PatentBrief.

- [How Roche Engineers Antibodies to Target Two Different Diseases Simultaneously](https://patentbrief.org/patent/us/10138293/opdivo-nivolumab) — granted 2018
  A method for creating a custom-engineered antibody that can grab onto two different targets at once, designed to help the immune system fight complex diseases.
- [How an Enzyme Helps Find Specific DNA in a Sample](https://patentbrief.org/patent/us/5210015/hcv-pcr-detection) — granted 1993
  This patent describes a method for detecting a specific DNA sequence in a sample by using a labeled DNA probe and an enzyme that cuts the probe, releasing detectable fragments.
- [Using PCR to Detect Viruses in Blood and Tissue Samples](https://patentbrief.org/patent/us/5176995/hiv-pcr-detection) — granted 1993
  A 1989 patent by Nobel laureate Kary Mullis and his team on using polymerase chain reaction (PCR) to replicate and detect tiny amounts of viral DNA or RNA, such as HIV and Hepatitis B, directly from human clinical samples.

**Full profile:** https://patentbrief.org/company/hoffmann-la-roche-inc

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_Source: PatentBrief — https://patentbrief.org. Plain-English explanations of US patents._